Drug Utilization Evaluation On Antidiabetic, Thyroid And Antithyroid Drugs
نویسندگان
چکیده
منابع مشابه
Thyroid and Antithyroid Drugs
Three hormones, thyroxine (3,5,3 ,5 -tetraiodothyronine, or T4), triiodothyronine (3,5,3 -triiodothyronine, or T3), and calcitonin (see Chapter 66) are secreted by the thyroid gland. The hormones T4 and T3 are iodinecontaining amino acid derivatives and are unique in that they have no discrete target tissue. Every tissue in the body is affected in some way by thyroid hormones, and almost all ce...
متن کاملAntithyroid Drugs
The thionamide drugs, i.e. carbimazole and its metabolite methimazole (MMI), andpropylthiouracil (PTU) have extensively been used in the management of various forms ofhyperthyroidism over the past eight decades. This review aims to summarize different aspectsof these outstanding medications. Thionamides have shown their own acceptable efficacy andeven safety profiles in ...
متن کاملAntithyroid Drugs
The thionamide drugs, i.e. carbimazole and its metabolite methimazole (MMI), andpropylthiouracil (PTU) have extensively been used in the management of various forms ofhyperthyroidism over the past eight decades. This review aims to summarize different aspectsof these outstanding medications. Thionamides have shown their own acceptable efficacy andeven safety profiles in ...
متن کاملAntithyroid drugs
ArticleCopyright : Jastrzębska; licensee BioMed Central Ltd.2015 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cit...
متن کاملAntithyroid drugs inhibit thyroid hormone receptor-mediated transcription.
CONTEXT Methimazole (MMI) and propylthiouracil (PTU) are widely used as antithyroid drugs (ATDs) for the treatment of Graves' disease. Both MMI and PTU reduce thyroid hormone levels by several mechanisms, including inhibition of thyroid hormone synthesis and secretion. In addition, PTU decreases 5'-deiodination of T(4) in peripheral tissues. ATDs may also interfere with T(3) binding to nuclear ...
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ژورنال
عنوان ژورنال: Biomedical and Pharmacology Journal
سال: 2020
ISSN: 2456-2610,0974-6242
DOI: 10.13005/bpj/2059